The main area affected is between Durham and Darlington with services delayed or diverted.
A statement posted by LNER on social media said: “It is with sadness that due to a person being hit by a train, some services are cancelled, altered, or delayed.”
A subsequent statement said: “Due to a person being hit by a train the 05:39 Sunderland to Kings Cross will be diverted between Newcastle and Northallerton.
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“It will no longer call at Durham and Darlington.”
A social media statement from Northern Trains added: “Due to the police dealing with an incident near the railway between Durham and Darlington the line is blocked.
“Train services running through these stations may be cancelled, delayed or diverted via Hartlepool.”
Durham Constabulary and British Transport Police have been contacted for further details.