Wigan boss explains striker substitution against Leeds United ahead of Middlesbrough clash
Moore, who joined the Latics from Barnsley this summer, was substituted late on against Leeds on Saturday but manager Paul Cook says that was always part of the plan.
Wigan will have to cope without several first-team players, though, with Josh Windass, Anthony Pilkington and Joe Garner all sidelined through injury.
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Hide AdMidfielder Joe Williams will also miss the game after he was sent off against Leeds.
"We've planned to make a couple of changes going forward, but Kieffer being substituted on Saturday was all part of that plan to make sure he's available for Middlesbrough,” said Cook ahead of the game at the Riverside.
"We'll have a few lads playing together for the first time, but it's a good opportunity to continue to integration of the squad.
"It's been disappointing to have a few injuries recently with Josh, Pilks and Joe Garner missing, but they'll be back before we know it."
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Hide AdLike Boro, Wigan have suffered back-to-back defeats in the Championship following Saturday’s setback.
Boro head coach Jonathan Woodgate could be boosted by the return of defender Dael Fry who played 60 minutes for the under-23 side last week.
Left-back Hayden Coulson will miss the game with a thigh injury, though, and is expected to be unavailable for the next few weeks.