Dave Challinor’s side beat Aldershot Town 2-1 on the opening weekend of the 2020-21 National League season.
Now they make the trip to Derbyshire to face a Chesterfield side they beat 5-1 last time the sides met.
Pools will have Luke Molyneux misses out following his self-isolation period after testing positive for coronavirus. Striker David Parkhouse is also unavailable as he joins up with the Northern Ireland under-21s squad this week.
Scroll down and click through the pages to see our predicted Pools line-up for the game...
Pools will have Luke Molyneux misses out following his self-isolation period after testing positive for coronavirus. Striker David Parkhouse is also unavailable as he joins up with the Northern Ireland under-21s squad this week.