Former TNS striker Scott Quigley popped up with two second half strikes to pour yet more misery on his former boss Craig Harrison and Hartlepool United.
The frontman pounced on some schoolboy Pools defending in the second 45 to score two breakaway goals and ensure the hosts, backed by a near sell-out crowd, went nine without a win.
On the selection front Pools made three changes from the side beaten at Dagenham.
Louis Laing was recalled at the heart of the backline for the injured Michael Ledger, Nicky Featherstone returned to the midfield after a lengthy absence, with Devante Rodney partnering Jake Cassidy up top.
It was the opposition who started the brighter with Scott Boden's effort tipped around the post by Scott Loach, while the Wrexham striker almost turned home at the back post when Pools' defenders were seemingly allowing the ball to drift out.
Before the game a 0-0 looked the safest bet in this one, despite there being 14 places and 15 points between the sides.
Wrexham, despite sitting in fourth before kick-off, are one of the lowest scorers in the division, along with Pools.
Just the bottom four of the fifth tier have netted less than these two and it showed. Bar those opening exchanges chances were few and far between.
And even though Pools improved as the half wore on, seeing much more of the ball, they created little in terms of clear cut opportunities.
As much as the opening 45 was a bit of a damp squib on the park, given their focus off it, the second period started with a bang.
And Pools almost edged in front when a Nicky Deverdics free kick was nodded down by Cassidy for Liam Donnelly who crashed off the Wrexham bar.
It was no near, yet so far for Pools, who were punished soon after when a Blair Adams error was pounced on by Quigley who slotted past a helpless Loach for 1-0.
And the big frontman, on his Dragons debut, wrapped it up with another goal on the counter on 72, to end Pools' hopes of giving the packed Vic crowd something to cheer.