Middlesbrough boss Tony Pulis will hope his side can end a three-match losing streak.
We take a look at some of the big talking points ahead of the latest round of fixtures, as well as how Middlesbrough and their promotion rivals are shaping up.
Fifth-place Boro are anxiously looking over their shoulder following three defeats in a row. Meanwhile, top of the table Norwich will be bidding for their tenth straight league win in the tea-time kick-off.
Championship top scorer Teemu Pukki has scored 24 league goals this term. The Finn has not found the net in his last three league games though.
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Following their 1-0 defeat by Sheffield United, Leeds dropped out of the play-off places by a point. The Whites will hope to get back to winning ways against Millwall at Elland on Saturday.
The Blades now hold the second automatic promotion spot but will have to stay on their game to keep it. Sheffield United host play-off chasing Bristol City at Bramall Lane on Saturday.
The Boro midfielder helped Norwich win promotion in 2015 but will be out to stop his former employers at the Riverside. Howson has been a regular for the Teessiders this campaign, making 38 appearances in all competitions.
The Blues were hit with a nine-point penalty for breaching EFL profitability and sustainability rules. The decision means Birmingham are now just five points above the drop zone ahead of a trip to West Brom on Friday night.
Since the departure of Darren Moore, caretaker boss James Shan has guided West Brom to back-to-back wins. Recent results have given the Baggies, who sit fourth, a decent buffer ahead of the sides below them.
Villa moved into the play-off places with a 3-0 win over Middlesbrough before the international break. Dean Smith and his side will be looking to make it five wins in a row when they face Blackburn at Villa Park.
Preston are on the same number of points as Villa and haven't lost for 12 matches. Manager Alex Neil will expect his side to extend that run when they visit relegation-threatened Reading.
Just four points separate fifth-place Boro and 11th-place Nottingham Forest. In between those two sides, Aston Villa, Preston, Derby, Sheffield Wednesday are all fighting for a play-off spot.