Warnock won’t be able to call upon Hayden Coulson who is ill, or George Saville and Paddy McNair who are away on international duty.
Our Boro writer Joe Nicholson has picked the starting XI he thinks could play – scroll down and flick though our picture gallery to see if you agree:
9. CAM: Marcus Tavernier
Foreced his way into the side at the end of last season and has earned high priase from Warnock in recent months. Photo: Clive Brunskill
10. ST: Ashley Fletcher
Scored 13 goals in all competitions last season and finished as Boro's top scorer. Will be hoping to get off the mark this campaign against Shrewsbury. Photo: Alex Livesey
11. ST: Britt Assombalonga
Missed part of last season though injury but still scored 11 league goals. Looks set to lead the line with Fletcher this season. Photo: Jan Kruger