Boro drew 1-1 at QPR last time out and suffered an injury blow when defender Grant Hall limped off with a calf issue.
Our Boro writer Joe Nicholson has picked the side he would start against Barnsley – scroll down and flick though our picture gallery to see if you agree:
5. CB: George Friend
Looked rusty against Luton after making his first-team comeback. His return will be a boost though. Photo: Tony Marshall
6. LWB: Hayden Coulson
The only Boro player who came away with credit against Luton. Provides energy and pace on the left. Photo: Alex Davidson
7. CM: Paddy McNair
Disappointing against Luton after returning to his natural central midfield role. Was Boro's best player in that position at the start of the season. Photo: Mike Hewitt
8. CM: Lewis Wing
Scored two goals against Wigan last week, taking his tally to six this season. Photo: Getty Images