Boro were beaten 1-0 at Stoke on Saturday after defender Nathan Collins headed home the only goal of the game at the Bet365 Stadium.
Our Middlesbrough writer Joe Nicholson has picked the side he would start at Preston - scroll down and flick through the pages of our picture gallery to see if you agree:
9. RW: Duncan Watmore
Dropped out of the side against Stoke after his impressive performance against Swansea last week. Photo: PA
10. LW: Marvin Johnson
Boro's top scorer this season with four in all competitions. Photo: George Wood
11. ST: Britt Assombalonga
Has started the last two games on the bench after a tricky spell. Photo: Getty Images