Boro have slipped too far away from the play-off places to challenge for promotion this term, while key first-team players such as Dael Fry, Marcus Tavernier, Sam Morsy and Anfernee Dijksteel have been ruled out for the rest of the season.
Warnock will therefore be handing some of his younger players an opportunity in the next few weeks, with striker Josh Coburn, as well as midfielders Hayden Hackney and Connor Malley, training with the first team.
The Teessiders were beaten 2-0 at Barnsley last time out and have now gone four games without a win.
Warnock may also choose to change his side’s formation against QPR to play with a back three and wing-backs and match the visitors up.
Here’s who we think could start for Boro at the Riverside.
5. LB: Hayden Coulson
Started in a more advanced position against Hull but has also impressed at left-back this campaign. Photo: Frank Reid
6. CDM: Jonny Howson
May have to play at right-back if Spence isn't available. Has impressed in a holding midfield role since Warnock's arrival. Photo: Alex Livesey
7. CM: George Saville
Was a key player in the Stoke win when a box-to-box midfield role appeared to suit him. Photo: Alex Davidson
8. CM: Paddy McNair
Looked lively early on against Hull but faded as the match wore on. Has the attributes to excel in an advanced midfield role. Photo: Frank Reid