Pools trailed 3-1 with nine minutes remaining after goals from Taylor Charters, Manasse Mampala and Tristan Abrahams cancelled out Matty Daly’s first half strike.
But a fine goal from Luke Molyneux and a penalty from Fela Olomola forced a penalty shoot out which Carlisle won 4-3.
That sees Pools take a point away from the game while The Cumbrians claim two in the group stages.
Scroll down and click through the pages to reveal the Pools player ratings from the game…
That sees Pools take a point away from the game while The Cumbrians claim two in the group stages.