After a goalless first half, Tom Denton put the hosts ahead from the penalty spot before a Will Evans own goal and debut strike from Ryan Johnson turned things around quickly for Pools.
Scott Boden was shown a straight red card for the Spireites late on as Pools continued their perfect start to the season.
Scroll down and click through the pages to see our Pools player ratings from the match...
9. Claudio Ofosu - 7
Was dangerous when he opened his legs. Didn’t get enough of the ball in dangerous areas in the first half but was much improved after the break. Photo: Christopher Booth
10. Mason Bloomfield - 5
Had a couple of half chances before being withdrawn due to a suspected knock picked up in the first half. Photo: HUFC
11. Ryan Donaldson - 5
A quiet display from the Pools skipper who tried to make things happen down the right. Photo: Christopher Booth
12. Ryan Johnson (on for Liddle 28) - 7
Was unfortunate to concede a penalty but made amends with a strikers goal on his debut and could have scored another. One shaky moment at the back but was otherwise composed and will be delighted to have netted the winner. Photo: HUFC