Boro drew 1-1 at QPR last time out and suffered an injury blow when defender Grant Hall limped off with a calf issue.
Our Boro writer Joe Nicholson has picked the side he would start against Barnsley – scroll down and flick though our picture gallery to see if you agree:
1. GK: Aynsley Pears
Has started Boro's last 16 league games but could face competition following the arrival of Dejan Stojanovic. Photo: George Wood
2. RWB: Djed Spence
Was recalled to the starting XI against Luton. Will be hoping to rediscover his best form. Photo: Justin Setterfield
3. CB: Jonny Howson
Returned to centre-back against Luton. Wasn't his best display but it's a position he's performed well in this season. Photo: Alex Livesey
4. CB: Harold Moukoudi
Has shown flashes of potential in his three Boro appearances. Still adjusting to his new side though. Photo: John Walton