Boro recorded an impressive 2-1 win over Swansea last time out when Warnock changed formation to play with a back three and match up the opposition.
Our Middlesbrough writer Joe Nicholson has picked the side he would start at Stoke - scroll down and flick through the pages of our picture gallery to see if you agree:
5. LB: Marc Bola
Started as a left-sided centre-back against Swansea before returning to left-back in the second half. Was excellent throughout. Photo: Clive Brunskill
6. CM: Jonny Howson
Has started every league game this season and captained the team against Swansea. Photo: Getty Images
7. CM: George Saville
Was given a rest against Swansea and will be desperate to get his place back. Photo: Getty Images
8. RW: Duncan Watmore
Looked sharp and scored twice against Swansea last time out. Photo: PA