Boro recorded an impressive 2-1 win over Swansea last time out when Warnock changed formation to play with a back three and match up the opposition.
Our Middlesbrough writer Joe Nicholson has picked the side he would start at Stoke - scroll down and flick through the pages of our picture gallery to see if you agree:
9. CAM: Marcus Tavernier
Produced another good impressive performance against Swansea and is always full of energy in midfield. Photo: Getty Images
10. LW: Marvin Johnson
Boro's top scorer this season with four in all competitions. Photo: George Wood
11. ST: Chuba Akpom
Didn't get many chances against Swansea but made some intelligent runs to create space for Watmore to score. Photo: Getty Images