Scott Fletcher was aged 27 when he disappeared on May 11 in 2011, and was last believed to have been seen at around 8pm near the Jet garage on the A181 at Wheatley Hill.
Scott’s mum Julie Fletcher says the unanswered questions around his disappearance continues to impact her daily life.
She said: “After ten years of course I still want Scott to walk through the door any minute, but I have to accept the reality that after all this time, that’s not going to happen.
“More than anything I want to know where Scott is, so that I can bring him home. That would mean so much to me.
"I don’t need to know who has caused him harm, I need to know where he is.
"To not know where he is causes pain which is with me every minute of every day.”
Cleveland Police launched a murder investigation and have made several public appeals for information over the last ten years.
Seven men were arrested between December 2015 and January 2016 on suspicion of conspiracy to murder but were later released.
Officers believe that Scott was killed in the Durham area and his body was concealed shortly afterwards.
A £10,000 reward by Crimestoppers for information leading to the arrest and conviction of the person or people responsible for Scott’s murder still stands.
Senior Investigating Officer Detective Superintendent Phil Bond said: “Someone out there has the information that we need to find out what happened to Scott.
"For some reason that person, or people, have not come forward so far and that may be due to fear of coming forward.
“I want people to think about Julie and what the pain over the last ten years has done to her and the rest of the family.
"Their ongoing suffering can be brought to an end, and I am again appealing to anyone with information to come forward.”
DSI Bond stressed Crimestoppers is completely independent of the police and any information provided stays anonymous.
Anyone with information is asked to call Cleveland Police on 101, or Crimestoppers on 0800 555 111 or at www.crimestoppers-uk.org.