Boro recorded an impressive 2-1 win over Swansea last time out when Warnock changed formation to play with a back three and match up the opposition.
Our Middlesbrough writer Joe Nicholson has picked the side he would start at Stoke - scroll down and flick through the pages of our picture gallery to see if you agree:
. GK: Marcus Bettinelli
Has been Boro's first-choice stopper this season. Photo: Alex Pantling
. RB: Djed Spence
Played as a wing-back against Stoke but made play on the right of a four if Boro change shape again. Photo: Getty Images
. CB: Paddy McNair
Has played every minute of every league game this season. Photo: Alex Pantling
1. GK: Marcus Bettinelli
Has been Boro's first-choice stopper this season. Photo: Alex Pantling
2. RB: Djed Spence
Played as a wing-back against Stoke but made play on the right of a four if Boro change shape again. Photo: Getty Images
3. CB: Paddy McNair
Has played every minute of every league game this season. Photo: Alex Pantling
4. CB: Dael Fry
Produced another commanding display against Swansea against a potent forward line. Photo: PA